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PhD Anouk Schrantee


  • Position
  • Post-doctoral researcher
  • Field of interest
  • Functional brain activity
  • Institute
  • Spinoza Centre for Neuroimaging

Research statement

My main scientific interests and activities are directed towards investigating the effect of pharmacological and physiological interventions on functional brain activity and its behavioral and cognitive correlates. The advances in functional MRI have allowed us to study dynamic processes in the brain in response to a task, pharmacological challenge or physiological intervention. My research has focused specifically on pharmacological MRI (phMRI), a technique to investigate the brain’s functional response to a drug challenge. As such, phMRI is a translational tool useful for drug development to identify target areas as well as for monitoring treatment. In a clinical trial, I have applied this technique to assess the effects of Ritalin treatment of brain development in patients with ADHD (ePOD study). In addition to hemodynamic measures of functional activity, I am also interested in using magnetic resonance spectroscopy (MRS) to obtain more direct measures of neuronal and metabolic activity. Using these state-of-the-art imaging techniques I aim to further unravel the effect of pharmacological and physiological interventions on the interplay between neuronal activity, metabolism and cerebral blood flow.



Biographical notes

Anouk Schrantee received her PhD degree from the University in Amsterdam in 2016. She worked at the Biological Imaging Centre (Imperial College London) for the first year of her PhD focusing on preclinical MRI experiments. In 2012 she moved to Amsterdam to continue with her clinical MRI studies at the department of Radiology. In November 2015 she started working as a post-doctoral researcher on a collaborative project of the department of Radiology (AMC, Amsterdam) and the Swammerdam Institute for Life Sciences (SILS, UvA, Amsterdam) investigating the effects of exercise on neurogenesis, angiogenesis and cognition using MRI. She joined the Spinoza Centre in July 2017, while continuing her work at the Radiology department of the AMC.